The Cancer of the Pancreas Screening-5.
For additional information, please contact the Research Nurses:
- Caroline DePiano, RN, MSN; 610-738-2522
- Susan Metzger, RN, MSN; 610-738-2515
A Randomized Study of an eHEALTH Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Breast, Ovarian, Prostate and Pancreatic Cancer Patients.
For additional information, please contact the Research Nurses:
- Caroline DePiano, RN, MSN; 610-738-2522
- Susan Metzger, RN, MSN; 610-738-2515
A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients with Unresectable and Borderline Resectable Pancreatic Cancer.
For additional information, please contact the Research Nurses:
- Caroline DePiano, RN, MSN; 610-738-2522
- Susan Metzger, RN, MSN; 610-738-2515
Brief Summary:
Collection of clinical and genetic information on individuals with or at risk for hereditary gastrointestinal cancer or polyposis syndromes to facilitate research on gastrointestinal cancer and polyposis syndromes.
Being part of the registry will give our program the option to potentially contact you if and when the following opportunities arise:
- We have updated information on any of your genetic testing results.
- New testing options become available that may benefit you or your relatives.
- There are new research opportunities available that may benefit you or your relatives.
- There are new therapies that you may be eligible for.
- There are other new opportunities or advances related to your condition, genetic testing results, or your familial risk, that may benefit you or your family.
Follow-up:
You will be enrolled into the Gastrointestinal Cancer and Polyposis Registry indefinitely, or until you request removal from the registry.
Partial Eligibility Criteria:
- Personal or family history of gastrointestinal cancer,
- Hereditary gastrointestinal cancer susceptibility syndrome
- Gastrointestinal polyposis syndrome
Final eligibility assessment is done by the health care professionals associated with the trial.
For additional information, please contact the Research Nurses:
- Nona Blauvelt, RN, MSN, AOCN; 610-738-2522
- CarolAnn Hoppes, RN, MSN; 610-738-2515
UPCC 4194 Identification and Analysis of Families with Genetic Susceptibility to Cancer
Purpose:
To collect DNA (blood sample) and data from families and/or individuals with tumors suggestive of inherited cancer conditions in order to further characterize inherited genetic variation.
All Patients:
- Blood sample for genetic analysis
- Written questionnaire about your medical history and your family history of cancer.
- Participants will have the option of learning any test results if they are felt to be potentially clinically relevant when they become available. Follow-up genetic counseling will be offered at no cost to the patient
Partial Eligibility Criteria:
- Individuals with a cancer diagnosis and
- A high risk tumor
- A family or personal medical history of neoplasia of an unusual type, pattern, or number; or
- Known or suspected factor(s) predisposing to neoplasia, either genetic and/or congenital factors, environmental exposure, or unusual demographic features.
- Types of familial tumors that we are currently actively accruing include breast, ovarian, and colon.
For additional information, please contact the Research Nurses:
- Nona Blauvelt, RN, MSN, AOCN; 610-738-2522
- Susan Metzger, RN, MSN; 610-738-2515